thinkpool

Nasty new Covid variant newly discovered in South Africa. It could escape vaccines and antiviral mAbs entirely. Lenz is variant agnostic because it isn't an antiviral. Lenz is an immunomodulator that only dampens the body's immune response preventing the body from attacking itself. Lenz will work equally well on this and all future variants. Since Covid is looking like it could be endemic, lenz might be used for decades. GM-CSF is the key to stopping the cytokine storm.

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Tom Peacock @PeacockFlu

https://twitter.com/georgimarinov/status/1463280142839468036

Just spotted: very small cluster of variant associated with Southern Africa with very long branch length and really awful Spike mutation profile including RBD - K417N, N440K, G446S, S477N, T478K, E484A, Q493K, G496S, Q498R, N501Y, Y505H

https://github.com/cov-lineages/pango-designation/issues/343

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Georgi Marinov @georgimarinov

https://twitter.com/georgimarinov/status/1463280142839468036

This has as many mutations as the worst of the WNY sequences from NYC's sewers.

And that one was actually tested for neutralization and did show complete total escape against all three class of RBD antibodies, it wasn't just a guess.

This is bye-bye-vaccine-level bad.

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Georgi Marinov @georgimarinov

https://twitter.com/georgimarinov/status/1463280142839468036

Quite the opposite.

This looks basically like SARS-CoV-3.

With zero cross-neutralization, is this even directly competing with Delta rather than being a new virus?

And they just posted 10 new such sequences, all from Gauteng, where the fourth wave is starting...

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